Comfortis Feline Medication to treat fleas orally

More Information:
Brand Name
What happens if I miss a dose: Give the missed dose with food as soon as you remember and resume a monthly dosing schedule.
How should this medication be given: Give Comfortis chewable tablets with food. Give Comfortis chewable tablets once a month.
Cautions:
What is the most important information I should know about Comfortis: Comfortis is a prescription medication FDA approved for use in dogs and puppies and cats and kittens 14 weeks of age or older to kill fleas and prevent flea infestations for one month. Comfortis is available in a Yellow box for dogs 3.3 to 9 cats and lbs 2-4 lbs (90mg), Pink box for dogs 5 to 10 lbs and cats 4-6 lbs (140mg), Orange box for dogs 10.1 to 20 lbs and cats 6.1-12 lbs (270mg), Green box for dogs 20.1 to 40 lbs and cats 12.1-24 (560mg), Blue box for dogs 40.1 to 60 lbs (810mg), and Brown box for dogs 60.1 to 120 lbs (1620mg). Please note: Cats over 24 lbs should be administered the appropriate combination of tablets.
What is Comfortis: Comfortis is a chewable, synthetic beef flavored tablet (derived from pork protein and hydrolyzed soy) that is given to a dog or cat to kill fleas and prevent flea infestations for one month. Comfortis chewable tablets are for monthly use in puppies and dogs or cats and kittens 14 weeks of age and older.
What happens if I overdose the pet: Overdose of this medication is unlikely. If an overdose is suspected, contact your veterinarian or veterinary emergency room. Symptoms of overdose that may occur include vomiting.
What other drugs will affect Comfortis: Talk to your veterinarian before giving any prescription or over the counter medications.
How it works:
What should I discuss with my veterinarian before giving Comfortis to my pet: Tell your veterinarian if you are planning on breeding your pet. If your dog or cat has a history of seizures (epilepsy), tell your veterinarian.
The FDA has received reports of adverse reactions in dogs receiving the drug Comfortis (spinosad) concurrently with high, extra-label doses of ivermectin. What is the most important information I should know about Comfortis: Comfortis is a prescription medication FDA approved for use in dogs and puppies and cats and kittens 14 weeks of age or older to kill fleas and prevent flea infestations for one month. Comfortis is available in a Yellow box for dogs 3.3 to 9 lbs and cats 2-4 lbs (90mg), Pink box for dogs 5 to 10 lbs and cats 4-6 lbs (140mg), Orange box for dogs 10.1 to 20 lbs and cats 6.1-12 lbs (270mg), Green box for dogs 20.1 to 40 lbs and cats 12.1-24 (560mg), Blue box for dogs 40.1 to 60 lbs (810mg), and Brown box for dogs 60.1 to 120 lbs (1620mg). How should this medication be given: Give Comfortis chewable tablets with food. Continue giving Comfortis chewable tablets and talk to your veterinarian if your pet experiences decreased appetite, lethargy or decreased activity, diarrhea, cough, increased thirst, vocalization, increased appetite, redness of the skin, hyperactivity and excessive salivation.
Generic Name.
What should I avoid while giving Comfortis: Your pet may maintain normal activities and interactions while being given Comfortis. The safe use of Comfortis in breeding, pregnant, or lactating cats and dogs has not been evaluated.
Comfortis (Lilly).
Spinosad.
Where can I get more information: Your pharmacist has additional information about Comfortis written for health professionals that you may read.
What are the possible side effects of Comfortis: Side effects that may occur include vomiting. Redose with another full dose if vomiting occurs within one hour of administration. Other side effects may occur. Continue giving Comfortis chewable tablets and talk to your veterinarian if your pet experiences decreased appetite, lethargy or decreased activity, diarrhea, cough, increased thirst, vocalization, increased appetite, redness of the skin, hyperactivity and excessive salivation. Talk to your veterinarian about any side effect that seems unusual or especially bothersome to the pet.
The FDA has received reports of adverse reactions in dogs receiving the drug Comfortis (spinosad) concurrently with high, extra-label doses of ivermectin. Dogs receiving extra-label doses of ivermectin to treat non-responsive demodectic mange and other conditions have developed signs of ivermectin toxicity. In cats, the most common adverse reaction recorded in clinical trials was vomiting.
Spinosad kills fleas by causing excitation of the insect’s nervous system, leading to paralysis and rapid death.

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